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Moreover, the indole Main is substituted at R3 by using a carbonyl group which happens to be also bonded into a napthalene moeity. Napthalene is a bicyclic framework of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it as being a ketone. JWH-018 is surely an analog of THJ-018, through which the core indazole framework is substi